Fig. 3: AT7519 arrests glioblastoma cells at the G1/S and G2/M phases of the cell cycle. | Cell Death & Disease

Fig. 3: AT7519 arrests glioblastoma cells at the G1/S and G2/M phases of the cell cycle.

From: The CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest

Fig. 3

A, B After U87MG and U251 cells were treated with different concentrations of AT7519 for 48 h, the cell cycle distribution was detected by flow cytometry. C, D Western blot analysis of cell lysates treated with different concentrations of AT7519 for 48 h. Detection of G1/S and G2/M arrest-related proteins.

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