Fig. 7: KAT8 acetylation regulates migration and invasion of CRC cells. | Cell Death & Disease

Fig. 7: KAT8 acetylation regulates migration and invasion of CRC cells.

From: KAT8 acetylation-controlled lipolysis affects the invasive and migratory potential of colorectal cancer cells

Fig. 7

A HCT116 cells were transfected with pCMV-myc-vector, myc-KAT8-WT and myc-KAT8-2KR plasmids for CCK8 assay to generate a growth curve. B, C HCT116 cells were transfected with the plasmids mentioned above, colony formation assay was performed to identify visible colonies. D, E HCT116 cells were treated with PA at 0.2 mM for 24 h and 48 h. A wound-healing assay was performed to evaluate the migration ability of cells. F-I HCT116 (F, G) and RKO (H, I) cells were transfected with the plasmids mentioned above, and treated with or without PA at 0.2 mM for 24 h. A wound-healing assay was performed to evaluate the migration ability of cells. J-M HCT116 (J, K) and RKO cells (L, M) were transfected with the plasmids mentioned above, a transwell assay was performed to evaluate the invasive ability of cells. The bar (−) represents the means (n = 3).

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