Fig. 1: Extraction of cytoskeleton-related gene signature and construction of cytoskeleton-related risk scoring model. | Cell Death & Disease

Fig. 1: Extraction of cytoskeleton-related gene signature and construction of cytoskeleton-related risk scoring model.

From: ASAP1 activates the IQGAP1/CDC42 pathway to promote tumor progression and chemotherapy resistance in gastric cancer

Fig. 1

A Co-differential expressed genes in GSE13911, GSE63089, and GSE65801 datasets. B The intersection of survival-associated differential-expressed cytoskeleton-related gene signatures in GSE66229 and GSE15460 datasets. Expression profile of 25 survival-associated cytoskeleton-related gene signatures in GSE13911 (C), GSE63089 (D), and GSE65801 (E) datasets. F Cytoskeleton-related risk scoring model constructed for predicting the overall survival of patients with GC. Receiver Operator Characteristic (ROC) curve of cytoskeleton-related risk scoring model predicting the 1-, 3-, and 5-year overall survival of GC patients in the training (G) and validation (H) cohort. Kaplan–Meier analysis for GC patients between high- and low- cytoskeleton-related risk groups in the training (I) and validation (J) cohort. ns-not significant; *p < 0.05; **p < 0.01; ***p < 0.001.

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