Fig. 4: Abolishing expression of DPT promotes BC cell growth, migration, and invasion.
From: DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP
a The protein levels of DPT in BT549 and MDA-MB-231 cells with DPT knockout were measured by western blotting. b CCK-8 assays were performed to detect the proliferative capacity of BT549 and MDA-MB-231 cells with DPT knockout. c Colony formation assays were conducted to determine the colony-forming abilities of BT549 and MDA-MB-231 cells with DPT knockout. d Transwell migration assays were conducted to detect the migratory abilities of BT549 and MDA-MB-231 cells with DPT knockout. e Transwell invasion assays were conducted to detect the invasive abilities of BT549 and MDA-MB-231 cells with DPT knockout. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
