Fig. 4: Calcineurin is the calcium effector mediating TRPM7 signaling in glycolysis. | Cell Death & Disease

Fig. 4: Calcineurin is the calcium effector mediating TRPM7 signaling in glycolysis.

From: The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis

Fig. 4

A [Ca2+]i changes in WT and TRPM7KO cells induced by naltriben (25 μM) (n = 6). B–D Naltriben-induced (25 μM, 4 h) SLC2A3 boost counteracted by preincubation of BAPTA-AM (50 μM, 1 h), FK506 (1 μM, 1 h) or CsA (1 μM, 1 h). Multiple groups were compared by ANOVA.

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