Fig. 3: KLF6 overexpression ameliorates hepatocellular injury and inflammation induced by hepatic I/R. | Cell Death & Disease

Fig. 3: KLF6 overexpression ameliorates hepatocellular injury and inflammation induced by hepatic I/R.

From: KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy

Fig. 3

a, b Verification of KLF6 overexpression after tail vein injection of adenoviruses by RT-qPCR and western blotting analysis. c Liver sections were stained by H&E staining, with the outlined areas showing hepatic necrosis. Scale bar, 500 μm. d Serum ALT/AST/LDH was detected after hepatic I/R surgery. e, f Neutrophils (Ly6G+) and macrophages (F4/80+) were identified. Scale bar, 50 μm. g Representative images of the TUNEL staining. Scale bar, 20 μm. Each group includes six mice. Mean values ± SD are shown, and statistical significance was determined by two-tailed Student’s t test. *p < 0.05.

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