Fig. 9: The expression of KLF6 associates significantly with liver function after clinical liver transplantation.
From: KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy
a RT-qPCR detection of KLF6 gene expression in liver tissues pre- and post-orthotopic liver transplant (OLT). b Western blotting analysis of KLF6 in liver tissues pre- and post-OLT. c Correlation analysis between post-OLT KLF6 mRNA levels and postoperative serum ALT and AST (POD0). d Patients were divided into high and low expression group according to the median of post-OLT KLF6 mRNA levels. e Comparison of serum ALT and AST levels (POD0) between KLF6 low expression group and KLF6 high expression group. f The line chart of the change of serum ALT and AST with postoperative days (POD) in the KLF6 low expression group and KLF6 high expression group. g Schematic illustration of the mechanism of KLF6 regulating liver ischemia-reperfusion injury. Mean with interquartile range are shown, and statistical significance was determined by Wilcoxon matched-pairs signed rank test (a), two-sided non-parametric Spearman rank correlation tests (c) or Mann–Whitney U tests (e, f). *p < 0.05.
