Fig. 3: The relationship between ufmylation of RPL10 and the stemness of PANC-1 cells.
From: The ufmylation modification of ribosomal protein L10 in the development of pancreatic adenocarcinoma
A Sphere formation of PANC-1 cells and Mia PaCa-2 cells after the knockdown of UFL1. B Sphere formation of PANC-1 cells and Mia PaCa-2 cells after the overexpression of UFSP2. C The populations of ALDH1+ cells and CD44+-CD24+ cells in PANC-1 and Mia PaCa-2 cells after the knockdown of UFL1. The populations were analyzed by flow cytometry (n = 3). D The populations of ALDH1+ cells and CD44+-CD24+ cells in PANC-1 and Mia PaCa-2 cells after overexpressing UFSP2. The populations were analyzed by flow cytometry (n = 3). All experiments were independently repeated for 3 times, and the data are expressed as mean ± SD. *P < 0.05 indicates statistically significant versus negative control. **P < 0.01 indicates statistically very significant versus negative control.
