Fig. 4: Identification of transcription factor KLF4 in PRL10 ufmylation related stemness of pancreatic cancer cells.
From: The ufmylation modification of ribosomal protein L10 in the development of pancreatic adenocarcinoma
A The correlation between stemness related transcription factors and UFM1 in tissues of PAAD patients (http://gepia2.cancer-pku.cn/#correlation). B The correlation between stemness related transcription factors and RPL10 in tissues of PAAD patients (http://gepia2.cancer-pku.cn/#correlation). C The relationship between the development of PAAD and gene transcripts of transcription factors (http://gepia2.cancer-pku.cn/#analysis). TPM is the abbreviation of transcripts per million of genes. D Protein expression of different transcription factors after the knockdown of UFL1 in PANC-1 and Mia PaCa-2 cells. E Protein expression of different transcription factors after the overexpression of UFSP2 in PANC-1 and Mia PaCa-2 cells. All experiments were independently repeated for 3 times.
