Fig. 5: Confirmation of the involvement of UFL1 in tumorigenesis and cell stemness in vivo.
From: The ufmylation modification of ribosomal protein L10 in the development of pancreatic adenocarcinoma

A The effects of the knockdown of UFL1 on tumor growth. Each group contained 8 mice, and data are expressed as mean ± SD. *P < 0.05 indicates statistically significant versus negative control. **P < 0.01 indicates statistically very significant versus negative control. B The effect of UFL1 knockdown on tumor growth by Ki67 staining. C Examination of RPL10 ufmylation and KLF4 expression in tumor tissues by Co-IP and WB. Tumor tissues were randomly chosen from each group. D The effects of the knockdown of UFL1 on cell stemness related markers by immunochemical staining.