Fig. 3: LPS-Nb36 enhances activation and proliferation of CD8+ T cells in DC/tumor fusion + LPS-Nb36 treatment.

A The CD8+ T cells were stained with CFSE and co-culture with HepG2, A549 or MGC-803 cells, respectively, with LPS-Nb36, Nb36 or anti-CTLA-4 mAb for 5 days. CD8+ T cells alone as the blank control group(unprimed). The effector cells were stained with PE-conjugated anti-CD25 or anti-CD69 mAb and analyzed by flow cytometry for the activation. n = 3, **P < 0.01, ***P < 0.001. B The fluorescent intensity of CFSE in the effector cells was directly analyzed by flow cytometry for the proliferation. n = 3, **P < 0.01, ***P < 0.001.