Fig. 2: MSCs upregulate efferocytic receptor-pathways following efferocytosis. | Cell Death & Disease

Fig. 2: MSCs upregulate efferocytic receptor-pathways following efferocytosis.

From: Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling

Fig. 2

A ST2 experimental setup (B) Principal component analysis (PCA) of 3 and 24 h sorted efferocytic ST2 cells via bulk RNA sequencing. C Heat map and (D, E) read count of efferocytic and intracellular processing genes at 3 h or 24 h vs the control analyzed via a DESeq2 with a benjamini-hochberg FDR correction. F Schematic representation of primary mMSC experimental setup (G) Principal component analysis of 4 h sorted efferocytic mMSCs cells fed apoptotic thymocytes via bulk RNA sequencing. H Heat map and (I, J) Read count of efferocytic and intracellular processing genes at 4 h SCAT vs SC analyzed via a DESeq2 with a benjamini-hochberg FDR correction.

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