Table 1 Clinical characteristics of patient cohorts.
From: B cell-derived IL-10 promotes the resolution of lipopolysaccharide-induced acute lung injury
Cohort: | Patients |
|---|---|
N | 9 |
Demographics: | |
Age (year) | 73.25 ± 6.16 |
Sexy (Male/Female) | 2/7 |
Underlying medical comorbidities, N (%) | |
Hypertensive disease | 5(55.6) |
Diabetes mellitus | 3(33.3) |
Coronary artery disease or congestive heart failure or myocardial infarction | 4(44.4) |
Chronic lung disease | 6(66.7) |
Cerebral infarction or Mental disorder | 5(55.6) |
Chronic kidney diseasea | 0 |
Clinical information on day of enrollment: | |
Hours from hospital arrival to enrollment | 20.06 ± 12.02 |
Hours from initial antibiotic initiation | 3.39 ± 1.24 |
Documented T ≥ 37 °C, N (%) | 9(100) |
Documented SBP < 90 mmHg, N (%) | 7(77.8) |
Vasopressor therapy within 48 h, N (%) | 5(55.6) |
SOFA scoreb | 8.22 ± 2.05 |
Oxygenation index | 156.22 ± 61.24 |
ARDS classificationc, (N) | |
Mild | 2 |
Moderate | 5 |
Severe | 2 |
Clinical lab index: | |
WBC Count (*109/L) | 23.37 ± 13.52 |
% Neutrophil | 101.23 ± 40.72 |
% Lymphocytes | 7.09 ± 5.51 |
% Monocytes | 13.56 ± 28.07 |
C reactive protein (mg/l) | 118.92 ± 91.78 |
Procalcitonin, PCT (ng/ml) | 3.14 ± 2.89 |
Serum lactate (mmol/dL) | 3.66 ± 1.96 |
Endotracheal intubation, N (%) | 6(66.7) |
Duration of mechanical ventilation (hours) | 108.50 ± 71.86 |
Clinical outcomes variables: | |
ICU stays (days) | 15.67 ± 6.16 |
Death during index illness and/or hospitalization, N (%) | 2(22.2) |
Second hospital admission within 30 days, N (%) | 1(14.3) |
Mortality(90-day), N (%) | 3(33.3) |
