Fig. 1: MGCG is overexpressed in GBM and leads to poor prognosis.
From: MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy
A Heatmap showing the differential expression of MGCG in the normal and GBM tissues. B The expression of MGCG was assessed in the normal and GBM tissues by RT‒qPCR (normal n = 22, GBM n = 47). C RT‒qPCR analysis of the relative expression of MGCG in HEB and GBM cell lines. (GBM cell lines: LN229, U251, T98G, U87, TJ905, and GOS3). D RT‒qPCR analysis of MGCG expression in the nuclear and cytoplasmic fractions of LN229 and U251 cells. E FISH analysis of MGCG expression in the nuclear and cytoplasmic fractions of LN229 cells. F FISH analysis of the relative expression of MGCG in the paraffin sections of the normal GBM tissues. G Kaplan‒Meier plots of overall survival of clinical patients with GBM with high and low levels of MGCG. Error bars, SEM from three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001 by two-tailed Student’s test.
