Fig. 4: The role of autophagy in promoting ferroptosis.
From: Autophagy mediates an amplification loop during ferroptosis
A, B NCOA4-mediated ferritinophagy (A) and Mitophagy (B) promote iron accumulation in ferroptosis. C–G Lipolysis mediated by lipases (C) and Hsc70/HSP90 chaperone-mediated autophagy (CMA) (D, E) and RAB7A-mediated macrolipophagy (F), and the cargo receptor SQSTM1-mediated clockophagy (G) promote lipid peroxidation in ferroptosis.
