Fig. 7: ApoExos show a specific profile of mRNAs. | Cell Death & Disease

Fig. 7: ApoExos show a specific profile of mRNAs.

From: Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis

Fig. 7

A Heatmap representation of protein-encoding RNA sequences and PCSK5 mRNA expression (TPM; transcripts per million) in ApoExos, ApoBodies, and endothelial cells under normal (HUVEC_N) or serum-starved (HUVEC_SS) conditions; n = 2. B Analysis of the percentage of mRNA identified in the transcriptome of ApoExos and present in the ExoCarta or Vesiclepedia databases. C Gene Ontology analysis of biological processes for mRNAs enriched in ApoExos (Table S2). Terms related to membrane depolarization, microtubule cytoskeleton, IgG-mediated phagocytosis, and vesicle targeting were enriched.

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