Fig. 8: Clinical relevance and individualized prognostic nomogram. | Cell Death & Disease

Fig. 8: Clinical relevance and individualized prognostic nomogram.

From: Clinical-mediated discovery of pyroptosis in CD8+ T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence

Fig. 8

A Forest plot of univariate Cox regression of the PRGs, including pyroptosis (GZMA and GSDMB) and clinical predicts (age, gender, pT/N/M-stage). B Forest plot of multivariate Cox regression of the PRGs, including pyroptosis (GZMA and GSDMB) and clinical predicts (age, gender, pT/N/M-stage). C K–M analysis showing the overall survival rate of high-risk patients (red) and low-risk patients (blue). The numbers of patients and the risk classification are indicated in the figure. D ROC curve was adopted to evolute the prediction performance of pyroptosis-related signature. E The individual prognostic nomogram of the 1-year, 2-year, and 3-year survival prediction of melanoma patients. F Calibration curve for the individual prognostic nomogram. A dashed diagonal line represents the ideal nomogram, and the blue line, red line, and orange line represent the 1-y, 2-y, and 3-y observed nomograms.

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