Fig. 1: HER2 expression in colon cancer patients and cell lines. | Cell Death & Disease

Fig. 1: HER2 expression in colon cancer patients and cell lines.

From: A HER2-targeting antibody-MMAE conjugate RC48 sensitizes immunotherapy in HER2-positive colon cancer by triggering the cGAS-STING pathway

Fig. 1

A Analysis of the immunohistochemical pathological reports for HER2 of 13 CRC patients in Jiangsu Provincial Hospital. B Western blot analysis of HER2 expression in murine and human CRC cell lines. C Expression and localization of HER2 detected by immunofluorescence on MC38HER2, MC38Ctrl, CT26HER2, and CT26Ctrl cells. D The mRNA expression of HER2 was measured by qPCR. **P < 0.01. E The expressions of HER2 on the cell membrane were detected using flow cytometry. F The expression and localization of HER2 in HCT116 and HT29 cells were determined by immunofluorescence. Scale bars, 10 μm.

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