Fig. 2: Decreased expression of AZGP1 in ICC patients predicts a poor prognosis. | Cell Death & Disease

Fig. 2: Decreased expression of AZGP1 in ICC patients predicts a poor prognosis.

From: AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway

Fig. 2

A AZGP1 mRNA expression was detected in cancer and adjacent tissues of 20 ICC patients by RT‒qPCR. B AZGP1 protein was detected in cancerous and adjacent tissues of 20 ICC patients by Western blotting. C The expression of the AZGP1 protein in normal tissue is strongly positive, and is divided into no expression, weak expression, and strong expression in tumor tissue. D The expression of AZGP1 was detected in ICC and normal tissues using immunofluorescence. E Kaplan‒Meier curves of OS of the AZGP1 expression group based on immunohistochemistry from the in-house cohort. F Kaplan‒Meier curves of RFS of the AZGP1 expression group based on immunohistochemistry from the inhouse cohort. ***p < 0.001, and ****p < 0.0001.

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