Table 1 AZGP1 levels and clinicopathological features in 74 ICC patients.
Variables | AZGP1 expression | |||
|---|---|---|---|---|
Total (n = 74) | Low expression (n = 54) | High expression (n = 20) | P value | |
Age, years, Mean ± SD | 65.81 ± 9.89 | 65.91 ± 9.81 | 65.55 ± 10.37 | 0.891 |
Gender, N (%) | ||||
Male | 31 (41.9) | 32 (59.3) | 11 (55.0) | 0.742 |
Female | 43 (58.1) | 22 (40.7) | 9 (45.0) | |
HBsAg, N (%) | 0.702 | |||
Negative | 47 (63.5) | 35 (64.8) | 12 (60.0) | |
Positive | 27 (36.5) | 19 (35.2) | 8 (40.0) | |
AFP, ng/mL, (IQR) | 2.76 (2.1–3.62) | 2.93 (2.09–3.7) | 2.7 (2.11–3.55) | 0.733 |
CEA, μg/L, (IQR) | 2.75 (1.65–7.63) | 2.85 (1.65–9.88) | 2.25 (1.55–4.18) | 0.461 |
CA19-9, U/mL, (IQR) | 104.85 (18.97–711.68) | 104.85 (18.97–857.93) | 111.65 (9.63–527.9) | 0.756 |
TNM Stage, N (%) | ||||
I-II | 58 (78.4) | 40 (74.1) | 18 (90.0) | 0.139 |
III-IV | 16 (21.6) | 14 (25.9) | 2 (10.0) | |
Tumor differentiation, N (%) | 0.588 | |||
Well | 52 (70.3) | 37 (68.5) | 15 (75.0) | |
Poor | 22 (29.7) | 17 (31.5) | 5 (25.0) | |
Tumor location, N (%) | ||||
Left | 46 (62.2) | 29 (53.7) | 17 (85.0) | 0.014 |
Right | 28 (37.8) | 25 (46.3) | 3 (15.0) | |
Tumor size, cm, N (%) | 0.872 | |||
≤5.0 cm | 47 (63.5) | 34 (63.0) | 13 (65.0) | |
å 5.0 cm | 27 (36.5) | 20 (37.0) | 7 (35.0) | |
Tumor number, N (%) | 0.48 | |||
Single | 66 (89.2) | 49 (90.7) | 17 (85.0) | |
Multiple | 8 (10.8) | 5 (9.3) | 3 (15.0) | |
Vascular invasion, N (%) | 0.321 | |||
No | 57 (77.0) | 40 (74.1) | 17 (85.0) | |
Yes | 17 (23.0) | 14 (25.9) | 3 (15.0) | |
Perineural invasion, N (%) | 0.934 | |||
No | 56 (75.7) | 41 (75.9) | 15 (75.0) | |
Yes | 18 (24.3) | 13 (24.1) | 5 (25.0) | |
Lymph node metastasis, N (%) | 0.147 | |||
No | 63 (85.1) | 44 (81.5) | 19 (95.0) | |
Yes | 11 (14.9) | 10 (19.5) | 1 (5.0) | |
AZGP1, N (%) | ||||
High | 20 (27.0) | 0 (0.0) | 20 (100.0) | |
Low | 54 (73.0) | 54 (100.0) | 0 (0.0) | |
Vital status, N (%) | 0.012 | |||
Alive | 35 (47.3) | 24 (44.4) | 11 (55.0) | |
Dead | 39 (52.7) | 30 (55.6) | 9 (45.0) | |
Diabetes, N (%) | ||||
No | 60 (81.1) | 41 (75.9) | 19 (95.0) | 0.063 |
Yes | 14 (18.9) | 13 (24.1) | 1 (5.0) | |
