Fig. 1: Sorcin expression, clinicopathological characteristics, and prognostic value in hepatocellular carcinoma (HCC). | Cell Death & Disease

Fig. 1: Sorcin expression, clinicopathological characteristics, and prognostic value in hepatocellular carcinoma (HCC).

From: Sorcin regulate pyroptosis by interacting with NLRP3 inflammasomes to facilitate the progression of hepatocellular carcinoma

Fig. 1

A Sorcin expression is higher in HCC (n = 371) than in normal liver tissues (n = 50) via the UALCAN database. B Sorcin expression was significantly associated with the advanced tumor-node-metastasis (TNM) stage. C The correlation between the transcriptional level of Sorcin and different tumor grades in HCC via the UALCAN database. D The association between Sorcin transcriptional level and tumor stages in HCC via the UALCAN database. E–H A Kaplan–Meier analysis of overall survival, progression-free survival, disease-specific survival, and relapse-free survival in HCC patients with high-Sorcin and low-Sorcin expression. I Immunohistochemical staining of Sorcin expression level was statistically higher in HCC tissues compared to adjacent tissues, and the staining results were statistically significant (n = 30). J–L Immunohistochemical staining of the pyroptosis-associated proteins was stained more lightly in HCC tissues than in adjacent tissues, including P20-Caspase-1, GSDMD-N, and IL-1β, and the difference was statistically significant. All *P < 0.05, **P < 0.01, ****P < 0.0001, and ns no significance.

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