Fig. 3: Sorcin regulates pyroptosis to promote HCC progression. | Cell Death & Disease

Fig. 3: Sorcin regulates pyroptosis to promote HCC progression.

From: Sorcin regulate pyroptosis by interacting with NLRP3 inflammasomes to facilitate the progression of hepatocellular carcinoma

Fig. 3

A Knockdown Sorcin increased pyroptosis-related proteins, whereas apoptosis-, ferroptosis-, and autophagy-related proteins were not significantly different from those in the control group at the protein level in HCC-LM3 and HuH7 cells. B–E The bar graph shows the relative protein levels of pyroptosis-, apoptosis-, ferroptosis-, and autophagy-related proteins from three independent experiments by western blot. F–J Overexpression of Sorcin reduced the expression of the pyroptosis-related proteins in HCC-LM3 and HuH7 cells. Data are indicated as mean±SD; multiple comparisons were performed using Two-Way ANOVA; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, and ns no significance.

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