Fig. 8: A working model.
From: Kindlin-2 in myoepithelium controls luminal progenitor commitment to alveoli in mouse mammary gland
Depletion of Kindlin-2 in myoepithelium activates the Jak2–Stat3–Dll1 axis, which activates Notch signaling in luminal progenitors and inhibits theirs differentiation and maturation during gestation.
