Fig. 3: QCCs could repopulate into PCCs.
From: Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells
A Dynamic streams predicted by RNA velocity analysis with a dynamical model. Arrows indicate the direction of the change in cell status based on the mRNA maturation in QCC and PCC groups. B Pseudotime predicted by the same workflow in (A). C A heatmap representation of the pseudotime inference shown in (A) and (B) in QCC and PCC groups. D Gene expression and phase portrait of cell-cycle activity markers MKI67 and CDK4. E Gene expression and splicing rate of cell-cycle inactive markers CDKN1A and CDKN1C. F Gene expression and splicing rate of QCCs-dependent markers ATF3.
