Fig. 1: FOXQ1 is overexpressed in PC tissues and cells. | Cell Death & Disease

Fig. 1: FOXQ1 is overexpressed in PC tissues and cells.

From: FOXQ1 promotes pancreatic cancer cell proliferation, tumor stemness, invasion and metastasis through regulation of LDHA-mediated aerobic glycolysis

Fig. 1

Screening of PC tissues for the EMT-related differentially expressed transcription factor FOXQ1 by public databases. A Consensus matrix heatmap defining two clusters (k = 2) and their correlation area. B Kaplan–Meier curve of clusters A and B. C Mapping of forest plots; FOXQ1 was upregulated in PC samples and subgroup A (high risk) and associated with prognosis. D Kaplan–Meier curve of 92 PC patients on the basis of IHC scores. E FOXQ1 relative expression was examined from GEPIA databases. F FOXQ1 expression level was assessed in 96 pairs of PC and adjacent tissues using IHC. G RT-qPCR assay was used to measure the mRNA level of FOXQ1 in 45 pairs of PC and adjacent tissues. H RT-qPCR assay was used to measure the mRNA level of FOXQ1 in the indicated cells. I Western blotting analysis of FOXQ1 expression in the indicated cells. Scale bar: 100 µm; *p < 0.05; **p < 0.01.

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