Fig. 8: TRIP12 controls metastasis of MDA-MB-231 cells.
From: Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12
A Bright field images of migrated MDA-MB-231 cells ± TGFβ treatment from indicated genotypes. B Quantification of migrated cells from 5 independent experiments in (A). C Western blot confirmation of TRIP12 overexpression in MDA-MB-231 cells from indicated genotypes. D Bright field images of migrated MDA-MB-231 cells ± TGFβ treatment from indicated genotypes. E Quantification of migrated cells from 4 independent experiments in (D). Statistics were done by One-way ANOVA. Each dot in the plots represents a mean value of cell count from 4–5 random images of migrated cells from each insert, p = * < 0.05, ** < 0.01, and # < 0.07.
