Fig. 5: Seahorse analysis of mitochondrial oxygen consumption rate (OCR) in MCL cells.

A OCR of JeKo-1 cells treated with AZD5991 (0.2 µM), venetoclax (1 µM), and their combination. B OCR of JeKo-IBN-R cells treated with AZD5991 (1 µM), venetoclax (2 µM), and their combination. C OCR of Mino cells treated with AZD5991 (0.1 µM), venetoclax (5 nM), and their combination. (D) OCR of Mino-VEN-R cells treated with AZD5991 (2 µM), venetoclax (0.2 µM), and their combination. AZD AZD5991; VEN venetoclax, Combo combination. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.