Fig. 7: STUB1 and GPX4 are independent prognostic factors for gastrointestinal stromal tumor (GIST). | Cell Death & Disease

Fig. 7: STUB1 and GPX4 are independent prognostic factors for gastrointestinal stromal tumor (GIST).

From: Imatinib induces ferroptosis in gastrointestinal stromal tumors by promoting STUB1-mediated GPX4 ubiquitination

Fig. 7

A Immunohistochemical analysis for the STUB1 and GPX4 expression in GIST tissue microarrays (n = 418). B Scatter plot showing a negative correlation between the expression of STUB1 and GPX4 in GIST. C Low STUB1 expression predicted poor recurrence-free survival (RFS) in GIST patients. D High GPX4 expression predicted poor RFS in GIST patients. E Nomogram for predicting the probability of recurrence in patients with GIST. F Calibration plot of the nomogram. Scale bar, 50 μm in A.

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