Fig. 5: Differential expression of pyroptosis-related proteins in the supernatants and low M1/M2 cells in vitro. | Cell Death & Disease

Fig. 5: Differential expression of pyroptosis-related proteins in the supernatants and low M1/M2 cells in vitro.

From: Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface

Fig. 5

A Differences in the protein expression levels of TRIM38, MITA, GSDMD, GSDMD-N, pro-caspase-1 and mature caspase-1 in the supernatants of M1 and M2 macrophages. B Differences in the protein expression levels of TRIM38 and MITA in M1 and M2 macrophages. C Differences in the mRNA expression levels of TRIM38 and MITA in M1 and M2 macrophages. D The higher expression of type UB and K48, but not K63, occurred in M1 compared to M2 macrophages. E The higher expression of MITA by ubiquitination of types UB and K48, but not K63, occurred in M1 compared to M2 macrophages. F The endogenous interaction relationship between TRIM38 and MITA in M1 and M2 macrophages. *P < 0.05, **P < 0.01.

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