Fig. 6: Exogenous interaction relationship among TRIM38 (Flag tag), MITA (HA tag) and K48 plasmid (His tag) in 293 T cells before and after knockdown of three domains. | Cell Death & Disease

Fig. 6: Exogenous interaction relationship among TRIM38 (Flag tag), MITA (HA tag) and K48 plasmid (His tag) in 293 T cells before and after knockdown of three domains.

From: Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface

Fig. 6

A Exogenous interaction relationship among TRIM38 (Flag tag), MITA (HA tag) and K48 plasmid (His tag). B Exogenous interaction relationship among knockdown of the ring finger structure of TRIM38 (Flag-TRIM38(d-RF)), MITA (HA-MITA) and K48 plasmid (His-K48). C Exogenous interaction relationship among knockdown of the B-box structure of TRIM38 (Flag-TRIM38(d-BB)), MITA (HA-MITA) and K48 plasmid (His-K48). D Exogenous interaction relationship among TRIM38 (Flag-TRIM38 (d-SP)), MITA (HA-MITA) and K48 plasmid (His-K48) with knockdown of the SPRY structure. E Expression validation of the type K48 ubiquitinated plasmid (His-K48) in 293 T cells (input).

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