Fig. 8: Lentiviral knockdown-related genes to verify the association among TRIM38, MITA, ubiquitination and pyroptosis. | Cell Death & Disease

Fig. 8: Lentiviral knockdown-related genes to verify the association among TRIM38, MITA, ubiquitination and pyroptosis.

From: Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface

Fig. 8

A Different ubiquitination levels of UB, K48, and K63 occurred in M1, shTRIM38-M1, shMITA-M1, shTRIM38+shMITA-M1 and M2, shTRIM38-M2, shMITA-M2, and shTRIM38+shMITA-M2 cells. B Differential expression of MITA by ubiquitination of types UB, K48, and K63 in M1, M2, shTRIM38-M1 and shTRIM38-M2. C Differences in the protein expression levels of TRIM38 and MITA in M1, shTRIM38-M1, shMITA-M1, shTRIM38+shMITA-M1 and M2, shTRIM38-M2, shMITA-M2, and shTRIM38+shMITA-M2 cells. D Differences in the protein expression levels of GSDMD-N in the supernatants of M1, shTRIM38-M1, shMITA-M1, shTRIM38+shMITA-M1 and M2, shTRIM38-M2, shMITA-M2, and shTRIM38+shMITA-M2 cells.

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