Fig. 3: Myofibroblast-specific BRG1 deletion attenuates liver fibrosis in mice.
From: The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis
The Postn-CreERT2; Smarca4f/f mice and the Smarca4f/f mice were subjected to CCl4 injection followed by tamoxifen injection. A Scheme of protocol. B Plasma ALT levels. C Plasma AST levels. D, E Expression levels of pro-fibrogenic genes were examined by qPCR and Western. F Picrosirius red and Masson’s trichrome staining. G Hydroxylproline quantification. N = 8 mice for each group. Data are expressed as the means ± SD. *p < 0.05.
