Fig. 3: TRIM65 deficiency promotes I/R-induced apoptosis in intestinal epithelial cells of mice. | Cell Death & Disease

Fig. 3: TRIM65 deficiency promotes I/R-induced apoptosis in intestinal epithelial cells of mice.

From: E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis

Fig. 3

A H&E staining and IHC staining of the intestine. Intestine tissues harvested 6 h after II/R were stained with H&E. IHC staining with TRIM65, BAX and Bcl2 was performed using the same intestine tissues. Scale bar, 100 μm. B The expressions of TRIM65, BAX, and Bcl-2 protein in the intestine after II/R were detected by western blot. Quantification of the bands was carried out using Gel-Pro Analyzer software, and results were presented as “fold changes” on the right side of the bands. C TUNEL staining of intestine in different groups. Scale bar, 100 μm. All results are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 by one-way ANOVA followed by Tukey’s test.

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