Fig. 2: CYLD induces high oxidative stress by regulating HDACs. | Cell Death & Disease

Fig. 2: CYLD induces high oxidative stress by regulating HDACs.

From: CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma

Fig. 2

a Venn plot showing the overlap of differential genes from different treatment groups. b differential genes from Venn plots were enriched by GO. c Representative IHC photographs showing the expression of CYLD and 8-OHdG in consecutive sections of NPC microarrays. d 8-OHdG level is calculated based on CYLD expression in NPC microarrays. e ROS levels of control and CYLD overexpressing HONE1-EBV cells were detected by FCM by using CellROX Deep Red. f ROS levels of HONE1-EBV cells with or without Chidamide treatment (0.5 μM) were detected by FCM by using CellROX Deep Red. g ROS levels of CYLD knockdown HONE1 cells with or without Chidamide treatment (0.5 μM) were detected by FCM by using CellROX Deep Red.

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