Fig. 1: INF2 expression is significantly up-regulated in EC and is associated with the clinical stage and unfavorable prognosis of patients with EC. | Cell Death & Disease

Fig. 1: INF2 expression is significantly up-regulated in EC and is associated with the clinical stage and unfavorable prognosis of patients with EC.

From: Phosphorylation of INF2 by AMPK promotes mitochondrial fission and oncogenic function in endometrial cancer

Fig. 1

A INF2 mRNA expression in normal endometrium tissues and tumor tissues of EC from TCGA EC cohort (http://ualcan.path.uab.edu/). B INF2 mRNA expression in different histological subtypes of EC from TCGA EC cohort. C INF2 mRNA expression in EC at different pathological stages from TCGA EC cohort. D Kaplan–Meier survival plots of OS according to INF2 mRNA expression in EC patients from the TCGA EC cohort. E Representative IHC images of INF2 staining in normal endometrium and EC tissues. F INF2 protein expression in normal endometrium tissues and EC tissues from our sample cohort. Data are medians ± interquartile range. G INF2 protein expression in EC at different FIGO stages from our sample cohort. Data are medians ± interquartile range. P values are calculated using the Student’s t-test in (A), the Kruskal–Wallis test in (B, C, G), and the Mann–Whitney test in (F). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Back to article page