Fig. 8: UFL1 overexpression rescues ER-phagy and mitigates ER stress and apoptosis. | Cell Death & Disease

Fig. 8: UFL1 overexpression rescues ER-phagy and mitigates ER stress and apoptosis.

From: DDRGK1-mediated ER-phagy attenuates acute kidney injury through ER-stress and apoptosis

Fig. 8

UFL1 plasmid was transfected to HK-2 cells to overexpress UFL1. A CCK-8 assay of UFL1 overexpression HK-2 cells with or without Iohexol. B–D The immunoblot analysis and quantification of UFL1, UFM1, and CANX in cell lysates. E–G The immunoblot analysis and quantification of GRP78 and CHOP in cell lysates. H, I The immunoblot analysis and quantification of BAX in cell lysates. Data are presented as the mean ± SEM (n = 3). *p < 0.05, **p < 0.01 and ***p < 0.001.

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