Fig. 5: scRNA-seq profiles subgroups of the B cell and T cell cluster. | Cell Death & Disease

Fig. 5: scRNA-seq profiles subgroups of the B cell and T cell cluster.

From: Single-cell RNA sequencing of cervical exfoliated cells reveals potential biomarkers and cellular pathogenesis in cervical carcinogenesis

Fig. 5

A Reclustering of B cells, color-coded by clusters (left) or group origin (right). B Average proportion of 10 subgroups of the B cell among NC, LSIL, HSIL, and CC samples. C Heatmap showing the differentially expressed genes (rows) of B cells across cluster (columns), with top genes indicated. D The t‐SNE plots of the B cell biomarkers. E Expression of cell motility-related genes (ACTB, ACTG1, and MYL6) in the subcluster of B cells. The dot size is proportional to the fraction of marker-expressing cells in the group. F Reclustering of T cells, color-coded by clusters (left) or group origin (right). G Average proportion of 15 subgroups of the T cell of NC, LSIL, HSIL, and CC samples. H Expression of T cell-specific markers across different clusters. The dot size is proportional to the fraction of marker-expressing cells in the group. I Violin plots showing the scores of functional modules for four groups, using the AddModuleScore function. *P < 0.05, **P < 0.01, ****P < 0.0001.

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