Fig. 7: Functional states of myeloid cells in the NC, LSIL, HSIL, and CC groups. | Cell Death & Disease

Fig. 7: Functional states of myeloid cells in the NC, LSIL, HSIL, and CC groups.

From: Single-cell RNA sequencing of cervical exfoliated cells reveals potential biomarkers and cellular pathogenesis in cervical carcinogenesis

Fig. 7

A The t‐SNE projection of myeloid cells demonstrating 12 main subclusters. B Average proportion of 12 subgroups of the myeloid cells among NC, LSIL, HSIL, and CC samples. C The t‐SNE plots showing the expression and distribution of APOE among myeloid cells. D Differences of M1/M2-like genes and cytokines between LAM and non-LAM. E Comparison of M1, M2, phagocytosis, and angiogenesis score between LAM and non-LAM. F Representative images for multiplexed immunofluorescence staining of LAM in NC, LSIL, HSIL, and CC tissues (CD163, red; APOE, green). DAPI was used to highlight all nucleus. G The expression of m6A methylation associated RNA transcripts between LAM and non-LAM. *P < 0.05, ***P < 0.001, ****P < 0.0001.

Back to article page