Fig. 8: Cell–cell communication among all cell types in the cervical exfoliated cells microenvironment.

A Circos plot showing the potential cell interactions among ten major cell types by CellphoneDB. Node size indicates interactions; edge width represents the number of significant ligand-receptor pairs. B Detailed view of the ligands expressed by each major cell types and the cells expressing the cognate receptors primed to receive the signal. C Heatmap depicting the significant ligand-receptor cellular interactions in different groups (The color bar represents the interaction counts between two different types of cells). D Dot plot indicating the ligand-receptor pairs between different cells. E t‐SNE plots showing the expression and distribution of SPP1 in the subcluster of macrophages, and CD44 in the subcluster of epithelial cells.