Fig. 8: Model for this study.
From: GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas

GINS2 regulates TMZ chemosensitivity of gliomas by participating in DDR through the EGR1/ECT2 axis, and GINS2 inhibitor (Palbociclib /BIX-02189) and TMZ synergistically inhibit glioma cell proliferation, stemness, invasion and migration capacity.