Fig. 3: Knockdown of FOXP3 inhibited the proliferation of GBM cell via inducing ferroptosis in vivo. | Cell Death & Disease

Fig. 3: Knockdown of FOXP3 inhibited the proliferation of GBM cell via inducing ferroptosis in vivo.

From: FOXP3 promote the progression of glioblastoma via inhibiting ferroptosis mediated by linc00857/miR-1290/GPX4 axis

Fig. 3

A, B Subcutaneous tumor formation assay was used to detect whether FOXP3 regulated U87 cell proliferation in vivo via a ferroptosis mechanism. C The weight of tumor tissues derived from U87 cells with FOXP3-knockdown or combined treatment with Fer-1. D The in situ tumor formation model was used to detect whether FOXP3 regulated U87 cell proliferation in vivo via a ferroptosis mechanism. E The expression of FOXP3, KI67, PCNA and GPX4 was detected in tumor tissues derived from U87 cells with FOXP3-knockdown or combined treatment with Fer-1 by IHC method. **P < 0.01.

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