Table 1 Univariate and multivariate analysis of different prognostic factors for overall survival in patients with LUAD.

Gender

Male

48 (53.3%)

Reference

Female

42 (46.7%)

0.885(0.528–1.484)

0.644

Age,year

<60

40 (44.4%)

Reference

≥60

50 (55.6%)

1.476(0.868–2.510)

0.150

T stage

T1-2

80 (88.9%)

Reference

T3-4

10 (11.1%)

3.473(1.666–7.238)

0.004

3.246 (1.329–7.928)

0.010

N stage

Negative

56 (62.2%)

Reference

Positive

34 (37.8%)

1.558(0.917–2.645)

0.101

Clinical stage

I -II

70 (77.8%)

Reference

III-IV

20 (22.2%)

2.482 (1.382–4.460)

0.002

1.251 (0.593–2.639)

0.556

Histologic grades

1–2

69 (76.7%)

Reference

3

21 (23.3%)

2.064(1.164–3.659)

0.013

1.282 (0.673–2.444)

0.450

TMEM9

Low

45 (50%)

Reference

High

45 (50%)

2.286(1.340–3.901)

0.002

5.925 (3.212–10.929)

0.001