Fig. 2: USP7 stabilized YY1 protein expression.
From: The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis
A–C The expressions of YY1 and USP7 at mRNA and protein levels were detected by qPCR and western blot with corresponding treatment in HCT116 cells. D–F The expressions of YY1 and USP7 at mRNA and protein levels were detected by qPCR and western blot with corresponding treatment in LOVO cells. G, H Effect of siUSP7 on YY1 degradation in HCT116 (G) and LOVO (H) cells transfected with siUSP7 and treated with CHX. I, G Effect of USP7 on YY1 degradation in HCT116 (I) and LOVO (J) cells transfected with siUSP7 and treated with MG-132. Data were expressed as the mean ± SD, ns, no significance,*P < 0.05, **P < 0.01, ***P < 0.001.
