Table 2 Univariate Cox regression analysis on overall survival and progression-free survival of colorectal cancer patients.
From: The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis
Variables | Overall survival | Progression-free survival | ||||
|---|---|---|---|---|---|---|
Hazard ratio | 95% CI# | P* | Hazard ratio | 95% CI# | P* | |
YY1 | ||||||
Low | 1.000 | Â | <0.001 | 1.000 | Â | <0.001 |
High | 4.520 | 2.170–9.413 |  | 4.020 | 2.154–7.500 |  |
Age | ||||||
≤55 years | 1.000 |  | 0.179 | 1.000 |  | 0.015 |
>55 years | 0.648 | 0.344–1.220 |  | 0.506 | 0.293–0.876 |  |
Gender | ||||||
Male | 1.000 | Â | 0.460 | 1.000 | Â | 0.303 |
Female | 1.264 | 0.679–2.353 |  | 1.332 | 0.772–2.297 |  |
Location | ||||||
Colon | 1.000 | Â | 0.877 | 1.000 | Â | 0.886 |
Rectum | 1.050 | 0.565–1.952 |  | 0.961 | 0.558–1.654 |  |
Tumor diameter | ||||||
≤5 cm | 1.000 |  | 0.960 | 1.000 |  | 0.962 |
>5 cm | 0.983 | 0.499–1.933 |  | 1.014 | 0.563–1.829 |  |
Differentiation | ||||||
Poor | 1.000 | Â | <0.001 | 1.000 | Â | <0.001 |
Moderate/high | 0.147 | 0.076–0.284 |  | 0.217 | 0.126–0.374 |  |
Lymph node metastasis | ||||||
Negative | 1.000 | Â | <0.001 | 1.000 | Â | <0.001 |
Positive | 4.048 | 2.093–7.829 |  | 5.631 | 3.091–10.258 |  |
Distant metastasis | ||||||
Negative | 1.000 | Â | 0.014 | 1.000 | Â | 0.005 |
Positive | 3.706 | 1.304–10.532 |  | 3.783 | 1.489–9.614 |  |
TNM stage | ||||||
I/II | 1.000 | Â | <0.001 | 1.000 | Â | <0.001 |
III/IV | 4.048 | 2.093–7.829 |  | 5.631 | 3.091–10.258 |  |
