Table 1 Potential application of EVs in GC immunotherapy.
From: Extracellular vesicles mediated gastric cancer immune response: tumor cell death or immune escape?
Potential drug or nano-preparation | Target immune cell | Treatment strategy based on EVs | Ref. |
|---|---|---|---|
LSD1 inhibitors | T cell | Target the production and cargo of EVs | [28] |
MLT | Macrophage | Target the production and cargo of EVs | [14] |
mJPYZ | Macrophage | Target the production and cargo of EVs | [56] |
iRGD-Exos-rMETase | DCs | EVs as drug carriers | [107] |
EVs-PD-1 antibodies and doxorubicin | DCs | EVs as drug carriers | [108] |
CDK-004 | Macrophage | EVs as drug carriers | NCT05375604 |
