Fig. 2: Single cell transcriptomics reveal FOXM1 as an OCSC-specific gene closely related to cell cycle progression. | Cell Death & Disease

Fig. 2: Single cell transcriptomics reveal FOXM1 as an OCSC-specific gene closely related to cell cycle progression.

From: Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness

Fig. 2

A UMAP representation of single cell data, mapping either the sample type (left panel), inferred cell cycle phases (middle panel) and FOXM1 expression (right panel). B Violin plot representing the level of expression of the FOXM1 gene in FOXM1 positive cells in the considered sample types (bulk OC in blue and OCSC in orange) divided by cell cycle phases (x axis). C UMAP representation of single cell data, mapping the expression of cell cycle related genes (AURKA, Aurora Kinase A, CCNB1, Cyclin B1, CDK1, Cyclin-dependent Kinase 1, PLK1, Polo-like Kinase 1).

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