Fig. 5: Obesity impairs mitochondrial function in human MSCs. | Cell Death & Disease

Fig. 5: Obesity impairs mitochondrial function in human MSCs.

From: Obesity-driven mitochondrial dysfunction in human adipose tissue-derived mesenchymal stem/stromal cells involves epigenetic changes

Fig. 5

Representative MitoSOX and tetramethylrhodamine ethyl ester (TMRE) staining (A) and quantification of mitochondrial reactive oxygen species (ROS) production (B), membrane potential (C), and ATP generation (D) in Non-obese- and Obese-MSCs untreated or treated with Bobcat339 or dimethyl alpha-ketoglutarate (DMĪ±KG) (nā€‰=ā€‰5 each). *p valueā€‰<ā€‰0.05 vs. non-obese-MSCs (untreated).

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