Fig. 7: HOXD10 overexpression restores renal function and kidney injury in UUO mice.
From: HOXD10 attenuates renal fibrosis by inhibiting NOX4-induced ferroptosis
A Schematic of the mouse experimental protocol. B Morphology of the kidney samples. C Ratio of obstructed kidney/body weight in mice. D Serum creatinine and E Serum BUN in various groups at 12 weeks of age. F Representative images of H&E, Masson’s trichrome and picro-sirius red stainings and relative tubular injury score and relative fibrotic area of each group (×400). Bar = 50 μm. In all panels, the data are representative of three independent experiments. Data are presented as the mean ± SD of each mouse (n = 10 mice in each group). **P < 0.01, NS not significant.
