Fig. 9: HOXD10 overexpression reduced ferroptosis and oxidative stress in UUO mice. | Cell Death & Disease

Fig. 9: HOXD10 overexpression reduced ferroptosis and oxidative stress in UUO mice.

From: HOXD10 attenuates renal fibrosis by inhibiting NOX4-induced ferroptosis

Fig. 9

A Iron concentrations in the kidney tissue lysates. B GSSG/total GSH ratio and C MDA and D SOD levels in the kidney tissues of each group. E DHE staining showed that AAV–HOXD10 alleviates ROS generation in UUO mice kidneys (×400). Bar = 50 μm. In all panels, the data are representative of three independent experiments. Data are presented as the mean ± SD of each mouse (n = 10 mice in each group). **P < 0.01, NS not significant.

Back to article page