Fig. 2: ALKBH4 promotes gastric cancer cell proliferation and inhibits gastric cancer cell pyroptosis in vitro. | Cell Death & Disease

Fig. 2: ALKBH4 promotes gastric cancer cell proliferation and inhibits gastric cancer cell pyroptosis in vitro.

From: ALKBH4 impedes 5-FU Sensitivity through suppressing GSDME induced pyroptosis in gastric cancer

Fig. 2

A Colony formation assay of gastric cancer cells treated with ALKBH4 overexpression or shALKBH4. B The proliferation curve of gastric cancer cells treated with ALKBH4 overexpression or shALKBH4. C, D Pyroptosis morphology of cells was observed under electron microscope (Red arrows indicate bubble-like structures). Scale bar is 50 μm. E, F Representative images of MKN45 and HGC-27 cells transfected with ALKBH4 shRNAs or control shRNAs were analyzed by transmission electron microscopy. The red arrow indicates the pores on the plasma membrane. The scale is 500 nm. Data are expressed as means ± standard errors of the means of three independent experiments, *P < 0.05, **P < 0.01.

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